A Comparative Study of Machine Learning Methods for Detecting Promoters in Bacterial DNA Sequences
نویسندگان
چکیده
Machine Learning methods have been widely used in bioinformatics, mainly for data classification and pattern recognition. The detection of genes in DNA sequences is still an open problem. Identifying the promoter region laying prior the gene itself is an important aid to detect a gene. This paper aims at applying several Machine Learning methods to the construction of classifiers for detection of promoters in the DNA of Escherichia coli. A thorough comparison of methods was done. In general, probabilistic and neural network-based methods were those that performed better regarding accuracy rate.
منابع مشابه
Protein Secondary Structure Prediction: a Literature Review with Focus on Machine Learning Approaches
DNA sequence, containing all genetic traits is not a functional entity. Instead, it transfers to protein sequences by transcription and translation processes. This protein sequence takes on a 3D structure later, which is a functional unit and can manage biological interactions using the information encoded in DNA. Every life process one can figure is undertaken by proteins with specific functio...
متن کاملA Comparative Study of SVM and RF Methods for Classification of Alteration Zones Using Remotely Sensed Data
Identification and mapping of the significant alterations are the main objectives of the exploration geochemical surveys. The field study is time-consuming and costly to produce the classified maps. Therefore, the processing of remotely sensed data, which provide timely and multi-band (multi-layer) data, can be substituted for the field study. In this study, the ASTER imagery is used for altera...
متن کاملA hybrid model based on machine learning and genetic algorithm for detecting fraud in financial statements
Financial statement fraud has increasingly become a serious problem for business, government, and investors. In fact, this threatens the reliability of capital markets, corporate heads, and even the audit profession. Auditors in particular face their apparent inability to detect large-scale fraud, and there are various ways to identify this problem. In order to identify this problem, the majori...
متن کاملAn Effective Method for Detecting Y-chromosome Specific Sequences of Circulating Fetal DNA in Maternal Plasma During the First-trimester
Background and Aims: New advances in the use of cell-free fetal DNA (cffDNA) in maternal plasma of pregnant women has provided the possibility of applying cffDNA in prenatal diagnosis as a non-invasive method. One of the applications of prenatal diagnosis is fetal gender determination. Early prenatal determination of fetal sex is required for pregnant women at risk of X-linked and some endocrin...
متن کاملEmotion Detection in Persian Text; A Machine Learning Model
This study aimed to develop a computational model for recognition of emotion in Persian text as a supervised machine learning problem. We considered Pluthchik emotion model as supervised learning criteria and Support Vector Machine (SVM) as baseline classifier. We also used NRC lexicon and contextual features as training data and components of the model. One hundred selected texts including pol...
متن کامل